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Search Results for " auristatin f "

8

Compounds

Cat No. Product Name Synonyms Targets
T14349 Auristatin F Microtubule Associated
Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.
T3256 MMAF MonoMethyl auristatin F Others , Microtubule Associated
MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.
T12081 MMAF-OMe Monomethyl auristatin F methyl ester
MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji ...
T18251 MAL-di-EG-Val-Cit-PAB-MMAF Others
MAL-di-EG-Val-Cit-PAB-MMAF refers to a chemical compound that comprises the linker (MAL-di-EG-Val-Cit-PAB) and the potent blocker of tubulin polymerization (MMAF, Monomethyl auristatin F)[1].
T18326 MC-Val-Cit-PAB-MMAF Others
MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavabl...
T27975 MAL-PEG4-MMAF
MAL-PEG4-MMAF is a maleimido functionalized derivative of MMAF (Monomethyl auristatin F) with PEG4 linker. The maleimido functional group can be easily conjugated to protein carriers (such as antibody or enzyme). MAL-PEG...
T77894 Val-Cit-PAB-MMAF sodium
Val-Cit-PAB-MMAF sodium is an agent-linker conjugate used in antibody-drug conjugates (ADCs), consisting of the peptide linker Val-Cit-PAB and the cytotoxic agent monomethyl auristatin F (MMAF), which inhibits tubulin po...
T77892 Mal-PEG8-Val-Cit-PAB-MMAF
Mal-PEG8-Val-Cit-PAB-MMAF is a drug-linker conjugate utilized for antibody-drug conjugates (ADCs), comprising a cleavable linker system and the potent tubulin inhibitor monomethyl auristatin F (MMAF), aimed at targeted c...
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